Summary: Publicly traded biotech is seeking Sr. Associate Engineer to contribute to the Polysaccharide Downstream Pilot Plant function within the CMC team. Biotech is developing a multi-valent polysaccharide-based conjugate therapy. Individual will have practical lab experience related to biotech, biopharmaceuticals, or vaccine industries, particularly around purification of macromolecules.Eager to learn utilize and apply new lab skills as this candidate will be responsible for collaboration on experimental design and execution of experiments at pilot scale for scale down modeling efforts and manufacturing program development. This role will require >50% time in the lab and this individual will be able to independently detail experimental procedures/results in written and presentation formats. The successful candidate will author detailed technical reports, present experimental results, and potentially interface with external CMO partners.Essential Functions:Perform downstream pilot scale experiments within DSP ops, focusing on the scale down model of the current manufacturing process, including all related set-up operations of buffer preps.Operate and maintain instrumentation for polysaccharide purification including Akta chromatography skids, depth filtration systems, TFF system and centrifuges.Analyze and interpret results for polysaccharide and impurity assays (SEC-MALS, HPAEC-PAD, Lowry, Anthrone etc.).Hold ccurate and current records of development experiments and/or project related activities in laboratory notebooks or electronic notebooks.Authoring/development of experimental protocols prior to experiment execution and respective results and reports.Present/communicate data to polysaccharide team.Works within a team environment and provides support as necessary to further the team’s initiatives.Requirements: BS in Chemical Engineering, Biochemistry, or a related discipline, with 5+ years of industry experience; MS with 3+ years of industry experience.Experience in supporting/execution of bioprocess operations such as Chromatography, depth filtration, TFF, and continuous centrifugation with a strong experience in these areas.Proficiency with engineering principles involved in scaling processes and transferring processes (pilot, manufacturing, lab).writing experimental protocols and summary reports. Benchling experience is a nice to haveFamiliarity with DoE (Design of Experiments) principles and ability to perform statistical data analysis with collected data.Process characterization experience is a nice to haveKnowledge of the requirements of GxP standards.Requires vaccination against COVID-19.Reports to: Associate Director, Pilot Plant and Manufacturing Location: San Mateo, CA Compensation:The compensation package will be competitive and includes comprehensive benefits and an equity component. Salary Range: $107,000 – $123,000 Compensation and benefits are aligned with the current market and commensurate with the person’s experience and qualifications, and the position's requirements.Enigma Search Solutions is an equal opportunity employer. We value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, gender expression, sexual orientation, age, marital status, veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform critical job functions, and to receive other benefits and privileges of employment.