Senior Scientist, In Vivo Cardiometabolic Diseases

Merck • South San Francisco, CA • Posted July 04, 2026

About the Role

**Job Description**

The Cardiometabolic Disease (CMD) department at our company's Research Labs South San Francisco is seeking a highly innovative and technically rigorous Scientist/Senior Scientist with deep expertise in preclinical in vivo models, particularly in cardiovascular and renal disease biology. This role is centered on hands-on ownership of complex rodent in vivo models and advanced physiological phenotyping to enable mechanistic discovery and target validation. The successful candidate will design, execute, and interpret sophisticated in vivo studies, often involving surgery, invasive measurements, and longitudinal functional readouts, and directly influence target selection and early translational strategy for cardio-renal programs.

The position requires a scientist who is deeply embedded in experimental execution, brings strong physiological intuition, and thrives in a discovery environment where in vivo data are the primary driver of scientific decisio...