Research Fellow (Single-molecule biophysics)

The Institute for Digital Molecular Analytics and Science (IDMxS) was officially launched on 1 December 2022 as a Research Centre of Excellence (RCE) supported by a total investment of around S$160 million over 10 years. IDMxS’ approach moves beyond simple intermolecular interactions in dilute media to embrace the inherent complexity of biological interactions and the dense heterogeneity of their environments. For more details, visit and

We are seeking a highly motivated and creative Research Fellow to join our team and lead an exciting project on how biomolecular condensates regulate enzyme function. The project employs quantitative single‑molecule approaches to link enzyme structure, dynamics, and kinetics in both condensate and dilute environments. By integrating complementary measurements across timescales, we investigate conformational state switching, reaction dynamics under non‑equilibrium conditions, and molecular mobility and permeability within dense phases.