Principal Scientist for Discovery Oncology

Eli Lilly and Company • remote, remote • Posted July 09, 2026

About the Role

Eli Lilly seeks a Principal Scientist in Toronto to advance new ligands for oncology programs. This role emphasizes cell-based assays and cross-functional collaboration.

As the Principal Scientist, you will innovate within discovery oncology at Eli Lilly. Your expertise in in vitro assays, mammalian cell culture, and microscopy will drive the characterization of potential radiopharmaceuticals. You'll partner closely with internal teams and external vendors, ensuring clear communication and timely results.

Key Responsibilities:
• Perform biochemical and cell-based assays independently
• Develop and optimize 2D and 3D functional cell lines
• Characterize compound affinity and internalization
• Collaborate with external partners to support discovery
• Assess and adapt experimental methods based on data

Requirements:
• Ph.D. in relevant scientific discipline or M.Sc with 3-5 years experience
• 3+ years of rele...